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24 past books matching Genetic Engineering

Wild Seed
Octavia E. Butler
Sci-Fi · Genetic Engineering
Wild Seed unfolds as a centuries-long confrontation between two immortals bound by power, desire, and control.

Wild Seed
Octavia E. Butler
Sci-Fi · Genetic Engineering · People of Color · Speculative Fiction
Our take
Wild Seed unfolds as a centuries-long confrontation between two immortals bound by power, desire, and control. Doro shapes humanity through ruthless breeding and domination, while Anyanwu builds communities through healing and care. When their paths collide, attraction becomes coercion and survival becomes negotiation. This novel explores immortality, consent, and legacy through an intimate struggle that reshapes generations.
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About the book
From the acclaimed author of the Earthseed series, two immortals chase each other across continents and centuries, binding their fates together and changing the destiny of the human race.
Doro knows no higher authority than himself. An ancient spirit with boundless powers, he possesses humans, killing without remorse as he jumps from body to body to sustain his own life. With a lonely eternity ahead of him, Doro breeds supernaturally gifted humans into empires that obey his every desire. He fears no one—until he meets Anyanwu.
Anyanwu is an entity like Doro and yet different. She can heal with a bite and transform her own body, mending injuries and reversing aging. She uses her powers to cure her neighbors and birth entire tribes, surrounding herself with kindred who both fear and respect her. No one poses a true threat to Anyanwu—until she meets Doro.
The moment Doro meets Anyanwu, he covets her; and from the villages of 17th-century Nigeria to 19th-century United States, their courtship becomes a power struggle that echoes through generations, irrevocably changing what it means to be human.
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She-Wolf and Cub
Lilith Saintcrow
Dystopian · Sci-Fi
A cyborg assassin breaks protocol when ordered to kill a child and instead escapes with him into a violent, post-apocalyptic world.

She-Wolf and Cub
Lilith Saintcrow
Dystopian · Sci-Fi · Genetic Engineering
Our take
A cyborg assassin breaks protocol when ordered to kill a child and instead escapes with him into a violent, post-apocalyptic world. Hunted by corporations and killers alike, she must survive long enough to protect the boy she chose to save. She-Wolf and Cub holds 4.3 stars on Amazon for its brutal action and heart.
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About the book
A cyborg assassin opts to save—not take—her target's life, in this post-apocalyptic adventure by the author of Afterwar and the Dante Valentine series.
Her name is unimportant. She is her job: a liquidator. Deep in debt for cyborg modifications, the agent eliminates whatever target she's given. It's a relatively simple job—until now. Her latest assignment is to kill a child, and she can't refuse—because refusal means Dismissal, a fate worse than death.
Instead, the operative smuggles her target out of the city, away from his corporate caretakers. But little Geoff is a gifted, genetically engineered, profitable experiment, and everyone—bounty hunters, fellow cyborgs, brain-fried cannibals, and other monsters—is desperate to get their hands on him.
The agent may be practically indestructible, but she's about to test her limits.
Hell hath no fury like a mother protecting her own . . .
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The Lost World
Michael Crichton
Speculative Fiction · Sci-Fi
Six years after the catastrophe at Jurassic Park, whispers emerge that dinosaurs may still roam a second, hidden island.

The Lost World
Michael Crichton
Speculative Fiction · Sci-Fi · Genetic Engineering
Our take
Six years after the catastrophe at Jurassic Park, whispers emerge that dinosaurs may still roam a second, hidden island. Drawn back into danger, scientists and explorers race to uncover the truth and survive the consequences of genetic engineering gone wrong. Michael Crichton’s The Lost World delivers relentless tension, breathtaking action, and the haunting question of what science has set loose.
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About the book
#1 NEW YORK TIMES BESTSELLER • From the author of Timeline, Sphere, and Congo comes the sequel to the smash-hit Jurassic Park, a thriller that’s been millions of years in the making.
“Fast and gripping.”—The Washington Post Book World
It is now six years since the secret disaster at Jurassic Park, six years since the extraordinary dream of science and imagination came to a crashing end—the dinosaurs destroyed, the park dismantled, and the island indefinitely closed to the public.
There are rumors that something has survived. . . .
“Harrowing thrills . . . fast-paced and engaging.”—People
“A very scary read.”—Entertainment Weekly
“Action-packed.”—New York Daily News
“An edge-of-the-seat tale.”—St. Petersburg Times
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The System Rises
Lucent Steele
Sci-Fi · Genetic Engineering
Human evolution takes a terrifying new shape when the world is forced to level up under rules no one can escape.

The System Rises
Lucent Steele
Sci-Fi · Genetic Engineering
Our take
Human evolution takes a terrifying new shape when the world is forced to level up under rules no one can escape. In The System Rises, a vanished futurist leaves behind a planetary framework of classes, races, and ruthless transformation, thrusting a selected team into the first test of what humanity might become. This LitRPG blends progression, high-stakes preparation, and questions of power, worthiness, and change.
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About the book
What if humanity’s next stage of evolution wasn’t discovered…
But engineered?
Elliot Voss spent decades pursuing a singular vision.
Until he found a way to rewrite the rules of life itself.
In secret, the billionaire futurist cured disease.
Then he cured aging.
Then… he vanished.
Now, without warning to anyone but a chosen few, the world is preparing to change.
The System will overlay the entire planet, bringing real stats, real levels, and three paths to evolution: Combat Class, Profession, and Race. But this isn’t a game. No do-overs. No respawns. And no one—not even the elite—is exempt.
As a handpicked team enters the first Tutorial shard, they must race to prepare Earth for its eventual induction into The System.
But Voss didn’t just want humanity to become stronger. He wanted it to become wiser. More compassionate. Worthy of the gifts to come.
In the end,
No one will remain unchanged.
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The Doors of Eden
Adrian Tchaikovsky
Sci-Fi · Genetic Engineering
Four years after vanishing on Bodmin Moor, Mal reappears, pulling her friend Lee—and MI5 investigator Julian Sabreur—into a mystery tied to physicist Kay Amal Khan’s research on parallel…

The Doors of Eden
Adrian Tchaikovsky
Sci-Fi · Genetic Engineering · Hard Sci-Fi · Space Opera
Our take
Four years after vanishing on Bodmin Moor, Mal reappears, pulling her friend Lee—and MI5 investigator Julian Sabreur—into a mystery tied to physicist Kay Amal Khan’s research on parallel Earths. As fractures between worlds widen and strange beings cross through, humanity faces threats it never imagined. Adrian Tchaikovsky delivers a tense, inventive multiverse adventure from an Arthur C. Clarke Award winner.
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About the book
From the Arthur C. Clarke Award-winning Adrian Tchaikovsky, The Doors of Eden is an extraordinary feat of the imagination and a page-turning adventure about parallel universes and the monsters that they hide. They thought we were safe. They were wrong. Four years ago, two girls went looking for monsters on Bodmin Moor. Only one came back. Lee thought she'd lost Mal, but now she's miraculously returned. But what happened that day on the moors? And where has she been all this time? Mal's reappearance hasn't gone unnoticed by MI5 officers either, and Lee isn't the only one with questions. Julian Sabreur is investigating an attack on top physicist Kay Amal Khan. This leads Julian to clash with agents of an unknown power - and they may or may not be human. His only clue is grainy footage, showing a woman who supposedly died on Bodmin Moor. Dr Khan's research was theoretical; then she found cracks between our world and parallel Earths. Now these cracks are widening, revealing extraordinary creatures. And as the doors crash open, anything could come through. "Tchaikovsky weaves a masterful tale... a suspenseful joyride through the multiverse." (Booklist)
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Homo Machina
PA Vasey
Sci-Fi · Genetic Engineering
In 2098, humanity is gone and Earth lies in radioactive ruin.

Homo Machina
PA Vasey
Sci-Fi · Genetic Engineering · Hard Sci-Fi
Our take
In 2098, humanity is gone and Earth lies in radioactive ruin. On Mars, synthetic humanoids search for meaning in the memories they no longer possess—until Sol-5 receives a desperate message from a surviving human. His journey to Earth reveals the truth behind humanity’s extinction and the danger that still lingers. A Global Book Awards gold medalist for dystopian sci-fi.
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About the book
GOLD MEDAL WINNER FOR DYSTOPIAN SCI-FI in the 2025 GLOBAL BOOK AWARDS
The year is 2098. Humanity is no more.
Earth is a ravaged, radioactive wasteland. On Mars, a small group of synthetic humanoids survive—their memories of the apocalypse wiped, seeking to understand their role in the fall of humanity.
Until Sol-5 receives a message. A message from a possible human survivor, and a plea to go to Earth to find her.
But what he finds there will change everything.
The humans were wiped out for a reason.
Homo Machina is the new post-apocalyptic thriller from the pen of award-winning author PA Vasey [Harbinger, Trinity Trilogy].
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Cascade Failure
L. M. Sagas
Sci-Fi · Genetic Engineering
Guild deserter Jal falls in with the oddball crew of the Ambit, a ship run by an AI and staffed by misfits who answer a distress call on…

Cascade Failure
L. M. Sagas
Sci-Fi · Genetic Engineering · Space Opera
Our take
Guild deserter Jal falls in with the oddball crew of the Ambit, a ship run by an AI and staffed by misfits who answer a distress call on a dead world. A lone survivor reveals a corporate plot that has already claimed multiple planets. Cascade Failure delivers fast paced sci fi with found family, danger, and heart.
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About the book
L. M. Sagas's debut, Cascade Failure, is a high-octane, sci-fi adventure blending J. S. Dewes's Divide series with Firefly. It features a fierce, messy, chaotic space family, vibrant worlds, and an exploration of the many ways to be—and not to be—human.
Most Anticipated Books of 2024—Goodreads, Polygon, The Nerd Daily
Best SFF Novels of 2024—Bookpage
There are only three real powers in the Spiral: the corporate power of the Trust versus the Union's labor's leverage. Between them the Guild tries to keep everyone's hands above the table. It ain't easy.
Branded a Guild deserter, Jal "accidentally" lands a ride on a Guild ship. Helmed by an AI, with a ship's engineer/medic who doesn't see much of a difference between the two jobs, and a "don't make me shoot you" XO, the Guild crew of the Ambit is a little . . . different.
They're also in over their heads. Responding to a distress call from an abandoned planet, they find a mass grave, and a live programmer who knows how it happened. The Trust has plans. This isn't the first dead planet, and it's not going to be the last.
Unless the crew of the Ambit can stop it.
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Imago
Octavia E. Butler
Dystopian · Sci-Fi
Good for readers who want thought-provoking science fiction about identity, evolution, genetic power, and the future of humanity.

Imago
Octavia E. Butler
Dystopian · Sci-Fi · Genetic Engineering
Our take
A child born from humans and aliens must confront a dangerous metamorphosis and bring humanity together, with a 4.5-star rating from more than 3,200 Amazon reviewers. Good for readers who want thought-provoking science fiction about identity, evolution, genetic power, and the future of humanity.
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About the book
After the near-extinction of humanity, a new kind of alien-human hybrid must come to terms with their identity—before their powers destroy what is left of humankind, in this thought-provoking science fiction novel from the New York Times bestselling author of Parable of The Sower.
Since a nuclear war decimated the human population, the remaining humans began to rebuild their future by interbreeding with an alien race—the Oankali—who saved them from near-certain extinction. The Oankalis' greatest skill lies in the species' ability to constantly adapt and evolve, a process that is guided by their third sex, the ooloi, who are able to read and mutate genetic code.
Now, for the first time in the humans' relationship with the Oankali, a human mother has given birth to an ooloi child: Jodahs. Throughout his childhood, Jodahs seemed to be a male human-alien hybrid. But when he reaches adolescence, Jodahs develops the ooloi abilities to shapeshift, manipulate DNA, cure and create disease, and more. Frightened and isolated, Jodahs must either come to terms with this new identity, learn to control new powers, and unite what's left of humankind—or become the biggest threat to their survival.
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Esperance
Adam Oyebanji
Sci-Fi · Mystery
A strong match for readers drawn to fast-paced science fiction mysteries involving impossible crimes, advanced technology, and competing ideas of justice.

Esperance
Adam Oyebanji
Sci-Fi · Mystery · Genetic Engineering
Our take
Called “[D]extrously blends genres in this suspenseful sci-fi mystery” by Publishers Weekly, Esperance follows Chicago detective Ethan Krol as he investigates a father and son found dead with seawater in their lungs, while in Bristol, Hollie Rogers befriends Abidemi Eniola, a mysterious woman with advanced technology and heirlooms to return. Their paths converge in a conflict over history and justice, with a 4.4-star rating from more than 350 Amazon reviewers. A strong match for readers drawn to fast-paced science fiction mysteries involving impossible crimes, advanced technology, and competing ideas of justice.
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About the book
**Los Angeles Times Book Prize Finalist**
"[D]extrously blends genres in this suspenseful sci-fi mystery.... Rob Hart and Blake Crouch fans should check this out." — Publishers Weekly
"Lovers of sharp, fast sci-fi from the likes of Neal Stephenson will be right at home with Esperance." —BookPage (starred)
A whip-smart thriller in the vein of Blake Crouch, Andy Weir, and Neal Stephenson, Esperance plumbs the depths of a seemingly impossible crime rooted in racism, intergenerational trauma, and an inhuman concept of justice
Detective Ethan Krol is on the twentieth floor of a Chicago apartment building. A father and son have been found dead, their lungs full of sea water—hundreds of miles away from the ocean.
Abidemi Eniola has arrived in Bristol, England. She claims to be Nigerian, but her accent is wrong and she can do remarkable things with technology, things that her new friend, Hollie Rogers, has never seen before. Abi is in possession of a number of heirlooms that need to be returned to their rightful owners, and Hollie is more than happy to go along for the ride.
But neither Abidemi Eniola nor her heirlooms are quite what they seem. Abi is a target of Ethan Krol’s investigations, and Hollie’s life is about to become far stranger than she bargained for. In a clash of cultures, histories, and different ideas about justice, the consequences will be deadly…
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Shards of Earth
Adrian Tchaikovsky
Sci-Fi · Genetic Engineering
A strong match for readers who like large-scale space opera, alien threats, damaged heroes, political pursuit, and found-family crews.

Shards of Earth
Adrian Tchaikovsky
Sci-Fi · Genetic Engineering · Speculative Fiction
Our take
Called “the breakout star of contemporary British SF” by the Guardian, Adrian Tchaikovsky follows Idris, an enhanced war hero living aboard a salvage vessel fifty years after the Architects destroyed Earth and vanished. When his crew discovers evidence of their return, they become targets for gangsters, cults, and governments, with a 4.5-star rating from more than 14,900 Amazon reviewers. A strong match for readers who like large-scale space opera, alien threats, damaged heroes, political pursuit, and found-family crews.
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About the book
The Arthur C. Clarke award-winning author of Children of Time brings us an extraordinary space opera about humanity on the brink of extinction, and how one man's discovery will save or destroy us all.
"Tchaikovsky is the breakout star of contemporary British SF." —Guardian
The war is over. Its heroes forgotten. Until one chance discovery ...
Idris has neither aged nor slept since they remade him in the war. And one of humanity's heroes now scrapes by on a freelance salvage vessel, to avoid the attention of greater powers.
After earth was destroyed, mankind created a fighting elite to save their species, enhanced humans such as Idris. In the silence of space they could communicate, mind-to-mind, with the enemy. Then their alien aggressors, the Architects, simply disappeared—and Idris and his kind became obsolete.Now, fifty years later, Idris and his crew have discovered something strange abandoned in space. It's clearly the work of the Architects—but are they returning? And if so, why?
Hunted by gangsters, cults and governments, Idris and his crew race across the galaxy hunting for answers. For they now possess something of incalculable value, that many would kill to obtain.
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Dawn
Octavia E. Butler
Sci-Fi · First Contact
Humanity survives, but not on its own terms, when Lilith wakes aboard an alien ship after nuclear war.

Dawn
Octavia E. Butler
Sci-Fi · First Contact · Genetic Engineering · People of Color · Speculative Fiction
Our take
Humanity survives, but not on its own terms, when Lilith wakes aboard an alien ship after nuclear war. In Dawn, Octavia E. Butler builds a post-apocalyptic story around coercion, survival, and the cost of starting over. It fits readers drawn to cerebral science fiction that uses first contact, genetic change, and social tension to probe power, identity, and what remains of the human future.
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About the book
One woman is called upon to rebuild the future of humankind after a nuclear war, in this revelatory post-apocalyptic tale from the award-winning author of Parable of the Sower.
When Lilith lyapo wakes from a centuries-long sleep, she finds herself aboard the vast spaceship of the Oankali. She discovers that the Oankali—a seemingly benevolent alien race—intervened in the fate of the humanity hundreds of years ago, saving everyone who survived a nuclear war from a dying, ruined Earth and then putting them into a deep sleep. After learning all they could about Earth and its beings, the Oankali healed the planet, cured cancer, increased human strength, and they now want Lilith to lead her people back to Earth—but salvation comes at a price.
Hopeful and thought-provoking, this post-apocalyptic narrative deftly explores gender and race through the eyes of characters struggling to adapt during a pivotal time of crisis and change.
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Adulthood Rites
Octavia Butler
Sci-Fi · Dystopian
Best for readers who like philosophical science fiction about alien contact, survival, identity, and the future of humanity.

Adulthood Rites
Octavia Butler
Sci-Fi · Dystopian · Genetic Engineering · Speculative Fiction
Our take
Adulthood Rites follows Akin, the first true human-alien hybrid born after nuclear war nearly destroys humankind and the Oankali save the survivors at a cost. As humanity resists a forced future of genetic merging, Akin must reconcile his divided heritage and decide what both species may become, with a 4.4-star rating from more than 2,900 Amazon reviewers. Best for readers who like philosophical science fiction about alien contact, survival, identity, and the future of humanity.
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About the book
From the award-winning author of Parable of the Sower: After the near-extinction of the human race, one young man with extraordinary gifts will reveal whether the human race can learn from its past and rebuild their future ... or is doomed to self-destruction.
In the future, nuclear war has destroyed nearly all humankind. An alien race intervenes, saving the small group of survivors from certain death. But their salvation comes at a cost.The Oankali are able to read and mutate genetic code, and they use these skills for their own survival, interbreeding with new species to constantly adapt and evolve. They value the intelligence they see in humankind but also know that the species—rigidly bound to destructive social hierarchies—is destined for failure. They are determined that the only way forward is for the two races to produce a new hybrid species—and they will not tolerate rebellion.
Akin looks like an ordinary human child. But as the first true human-alien hybrid, he is born understanding language, then starts to form sentences at two months old. He can see at a molecular level and kill with a touch. More powerful than any human or Oankali, he will be the architect of both races' future. But before he can carry this new species into the stars, Akin must reconcile with his own heritage in a world already torn in two.
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